Things To Avoid for Insulin Resistant, Cushings, or Founder Horses
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This is a partial list of suggested things to avoid for horses who tend to founder, have equine Cushings, or are insulin resistant.
Copyright 2005 Equine Cushings and Insulin Resistance group - Reprinted here with permission. http://pets.groups.yahoo.com/group/EquineCushings/
STEROIDS should be avoided in horses prone
to laminitis. This includes low dose administration for the Dex
Suppression Test. The exception would be in a life threatening
Antibiotics in the SULFA DRUG family (like the commonly used SMZ)
should be avoided in horses prone to laminitis because they can alter
GLUCOSAMINE - oral or injected should be avoided or used with extreme
caution in the laminitis prone horse.
With high dose ACE in a horse on Cushings medication, one should be
aware that ACE and pergolide (and Vitex) have opposing actions on
brain chemical dopamine. One could also speculate that high dose ACE
and high dose pergolide could lower blood pressure to an undesirable
New wormer drug PRAZIQUATEL should be avoided or used with extreme
caution (see FILES section of the EquineCushings list).
Herbal YUCCA, and possibly WILD YAM.
Long term/high dose use of NSAIDs like bute and banamine will of
course, increase the well know risks of ulceration of the stomach and
GI tract and possible kidney damage, but will also, over time
decrease circulation and healing by limiting blood gas Nitric Oxide.
If we have learned anything from our list member's horses it is that
horses prone to laminitis (Cushings or not) can be very sensitive to
stress and changes. Sensitivity to individual substances varies
If a horse is not stable, any and all drugs (including vaccinations
and wormers), feed additives, herbs and feeds should be viewed with
suspicion and reviewed.
A orderly, systematic elimination trial will often reveil a substance
the horse is sensitive to.
It is impossible to list all of the things suspected of causing
problems or make generalizations. A case by case, careful observation
of reactions should be employed.
Some general potential trouble feeds outside of the obvious of any
GRAIN PRODUCTS and SUGARS might include: Soy, clover, alfalfa, live
probiotics, yeast, seed meals, MSM and DMG.
Some horses thrive on the above, others cannot have them at all.
Try to avoid starting too many new things at once, and avoid multiple
challenges at once (for instance - doing a major teeth floating with
sedation should not be done on the same day necessary vaccines are
given; worming should be avoided right before a long trailer ride).
Vaccines should be discussed with Vet to access risks to the actual
diseases and kept to a minimum and well spaced out. A number of these
horses seem very sensitve to vaccinations.
Feed additives and herbs are variable too. Pause before adding
anything new to your horse's routine. When considering one, try to
establish its mode of action, and ask yourself how it might affect
the horse. Some herbs and supplements claim to "lower blood glucose
and improve diabetic conditions", but upon closer inspection we might
find that rather than helping with cell sensitivity to insulin, they
might stimulate pancreatic activity.
Be cautious of herbs that alter hormones unless it is something that
we know is helpful (like Vitex/Chasteberries), but be sure it is
indicated for your particular animal.
Then there are substances that may be helpful in some situations and
contraindicated in others:
Vitamin C is a wonderful, powerful antioxidant but should not be
supplemented when there is high iron in the diet.
Milk Thistle Seed is useful for liver protection and in blocking iron
absorption, but contains significant amounts of selenium that must be
factored in to the overall diet.
Specific amino acids can be very useful in diets with marginal
protein, but some specific animo acids stimulate a glycemic response
and need to be used with caution - likewise for chelated minerals as
they are chemically bound to amino acids.
Avoid significant amounts of fat/oils, high
nitrates and excess protein, and stress that these
will depend on individual sensitivities and situations.
With the laminitic horse, for me EVERYTHING needs to
be looked at because sometimes it is what you least